H. Nakano

Substrate profiling of human Transglutaminase 1 using cDNA display and next-generation sequencing

This study identifies substrate preferences of human transglutaminase 1 using cDNA display and next-generation sequencing, revealing a high-reactivity peptide and potential new substrates.

Rapid and cost-effective epitope mapping using PURE ribosome display coupled with next-generation sequencing and bioinformatics

The paper develops a cost-effective method for epitope mapping using PURE ribosome display combined with NGS and bioinformatics, identifying the 'DVPDY' epitope in hemagglutinin.

A high-sensitivity ELISA for detection of human FGF18 in culture supernatants from tumor cell lines

This paper develops a high-sensitivity ELISA for detecting human FGF18 in tumor cell culture supernatants and validates its use in detecting murine FGF18 in mouse sera.

Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy

The paper maps fetal metabolism during mid-to-late gestation in normal and diabetic pregnancies, identifying metabolic changes due to maternal hyperglycemia.

Nascent MSKIK peptide prevents or releases translation arrest in Escherichia coli

The paper shows that inserting the MSKIK peptide near a start codon enhances protein production in E. coli by preventing or releasing translational arrest.

A Shape Sensing Mechanism driven by Arp2/3 and cPLA2 licenses Dendritic Cells for Migration to Lymph Nodes in Homeostasis

The paper identifies a shape sensing mechanism in dendritic cells that links cell motility to CCR7 expression, enabling migration to lymph nodes through ARP2/3-cPLA2 signaling.

A FRET biosensor, SMART, monitors necroptosis in renal tubular epithelial cells in a cisplatin-induced kidney injury model

Cardio PyMEA: A user-friendly, open-source Python application for cardiomyocyte microelectrode array analysis

Cardio PyMEA provides a user-friendly, open-source Python tool for analyzing cardiomyocyte microelectrode array data, offering customizable functionalities and cross-platform accessibility.

cDNA display coupled with next-generation sequencing for rapid activity-based screening: Comprehensive analysis of transglutaminase substrate preference

The paper develops a cDNA display combined with next-generation sequencing platform to analyze transglutaminase 2 substrate preferences, revealing comprehensive amino acid preferences at specific peptide positions.

The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis

This study shows that RIPK1's scaffold function in dendritic cells prevents colonic inflammation and maintains immune homeostasis by inhibiting apoptosis and necroptosis.

Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer Progression

This study identifies IL-11 as a marker for fibroblasts involved in colorectal cancer progression, showing their role in tumor development through a feed-forward loop.

Multiple strategies for heat adaptation in rice endosperms revealed by on-site cell-specific analysis

This study reveals how rice endosperm cells adapt to heat stress through osmotic adjustments and nitrogen-dependent changes in organelle compartments, reducing chalkiness.