Author

J. Qiao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Bioengineering· 2 Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:metagenomics· 3 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

J. Li· 2 shared J. Zhang· 2 shared K. L. Meibom· 2 shared N. Jacquemin· 2 shared R. Bernier-Latmani· 2 shared W. Yin· 2 shared X. Wang· 2 shared Y. Chen· 2 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

J. Li

Mutual co-authors in cluster

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9 papers

Recent·Most cited

Growth substrate limitation enhances anaerobic arsenic methylation by Paraclostridium bifermentans strain EML

J. Qiao, H. Sallet, K. L. Meibom, N. Jacquemin, R. Bernier-Latmani

This study shows that growth substrate limitation enhances anaerobic arsenic methylation by Paraclostridium bifermentans strain EML through increased arsM gene expression and microbe-microbe competition.

Applied and Environmental Microbiology · Dec 18, 2024Peer-reviewedMicrobiology

A split crRNA with CRISPR-Cas12a enables highly sensitive, selective, and multiplexed detection of RNA and DNA

J. Qiao, Y. Chen, X. Wang, W. Yin, B. He, Y. Liu

This paper develops a split CRISPR-Cas12a system for sensitive, selective, and multiplexed detection of RNA and DNA without reverse transcription, achieving low detection limits and improved specificity.

bioRxiv · Jan 4, 2024 · PreprintBiochemistry

Spatially-resolved single-cell atlas of ascidian endostyle provides insights into the origin of vertebrate pharyngeal organs

A. Jiang, K. Han, J. Wei, X. Su, R. Wang, W. Zhang, X. Liu, J. Qiao, P. Liu, Q. Liu, J. Zhang, N. Zhang, Y. Ge, Y. Zhuang, H. Yu, , B. Dong

The paper constructs a spatially-resolved single-cell atlas of the ascidian endostyle, identifying new cell types and evolutionary insights into vertebrate pharyngeal organs.

bioRxiv · May 3, 2023Evolutionary Biology

Structure of a fungal 1,3-β-glucan synthase

C.-R. Zhao, Z.-L. You, D.-d. Chen, J. Hang, Z.-B. Wang, L.-X. Wang, P. Zhao, J. Qiao, C.-H. Yun, L. Bai

This study determines the cryo-EM structure of Saccharomyces cerevisiae 1,3-β-glucan synthase Fks1, revealing its catalytic mechanism and the role of disulfide bonds in enzymatic activity.

bioRxiv · Mar 19, 2023Biophysics

Activation of the chemokine receptor CCR1 and preferential recruitment of Gαi suppress RSV replication: implications for developing novel RSV treatment strategies

J. Li, L. Xue, j. c. wang, A. Meng, J. Qiao, M. Li, X. Wang, L. Meng, J. Ning, X. Gao, W. Li, C. Ma, L. Wei

This study shows that CCR1 activation on respiratory epithelial cells suppresses RSV replication via Gi-mediated inhibition of STAT3 phosphorylation and HSP90 activity, independent of IFN-I.

bioRxiv · Mar 18, 2022 · PreprintMicrobiology

Rational design of Cas9 ribonucleoprotein with a "gRNA-shRNA" for multidimensional genome manipulation and enhanced homology-directed repair

j. qiao, w. sun, w. yin, l. ma, y. liu

This paper develops a Cas9-RNAi RNP tool that combines RNAi and CRISPR for simultaneous gene knock out and knock down, and enhances homology-directed repair.

bioRxiv · Mar 17, 2022 · PreprintBioengineering

Meta-omics-aided isolation of an elusive anaerobic arsenic-methylating soil bacterium

K. Viacava, J. Qiao, A. Janowczyk, S. Poudel, N. Jacquemin, K. L. Meibom, H. K. Shrestha, M. C. Reid, R. L. Hettich, R. Bernier-Latmani

The paper isolates an anaerobic arsenic-methylating bacterium using meta-omics approaches to overcome challenges in functional isolate identification.

bioRxiv · Jan 25, 2022Microbiology

Rapid pacing by circulating traveling waves improves maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring

J. Li, L. Zhang, L. Yu, I. Minami, M. Horning, J. Dong, J. Qiao, N. Fujimoto, Y. Shiba, Y. Zhao, F. Tang, S. Miyagawa, Y. Chen, Y. Sawa, C. Tang, L. Liu

bioRxiv · Jul 27, 2019Bioengineering

Metatranscriptome profiling of the dynamic transcription of mRNA and sRNA of a probiotic Lactobacillus strain in human gut

Q. He, z. sun, J. Qiao, D. Chen, J. Huang, X. Luo, J. Ding, J. Zhang, Q. Hou, Y. Zhang, H. Zhang

This study uses metatranscriptomic sequencing to analyze the dynamic transcription patterns of an ingested Lactobacillus casei strain in the human gut, revealing significant changes in mRNA and sRNA expression over time.

bioRxiv · Oct 14, 2018 · PreprintMicrobiology