K. Han

Human umbilical mesenchymal stem cell-derived mitochondria ameliorate maternal phenotype by improving placental mitochondria and vascular function in angiotensin II-induced preeclampsia rat

This paper demonstrates that human umbilical mesenchymal stem cell-derived mitochondria transplantation improves placental mitochondrial function and vascular health, reversing preeclampsia symptoms in a rat model.

BLOC1S1 control of vacuolar organelle fidelity modulates TH2 cell immunity and allergy susceptibility.

This study shows that BLOC1S1 depletion disrupts mitochondrial integrity, leading to TH2 cell immunity and allergy susceptibility via STING-NF-κB signaling.

Spatially-resolved single-cell atlas of ascidian endostyle provides insights into the origin of vertebrate pharyngeal organs

The paper constructs a spatially-resolved single-cell atlas of the ascidian endostyle, identifying new cell types and evolutionary insights into vertebrate pharyngeal organs.

Surface-based Characterization of Gastric Anatomy and Motility using Magnetic Resonance Imaging and Neural Ordinary Differential Equation

This paper introduces a method using MRI and neural ODEs to model gastric motility and anatomy in rats, revealing functional regions and muscle activity patterns.

Amplification of Olfactory Signals by Anoctamin 9 is Essential for Mammalian Olfaction: a Risk Factor for the Covid-19-associated Anosmia

This study identifies Anoctamin 9 as essential for mammalian olfaction, showing its role in amplifying olfactory signals and linking its downregulation to Covid-19-associated anosmia.

Controlled adhesion, membrane pinning and vesicle transport by Janus particles

This study uses Janus particles to control adhesion and transport in artificial cell membranes through electrostatic and magnetic interactions.

Neurotoxic Amyloidogenic Peptides Identified in the Proteome of SARS-COV2: Potential Implications for Neurological Symptoms in COVID-19

The paper identifies amyloidogenic peptides in SARS-CoV-2 that are toxic to neuronal cells, suggesting they may contribute to neurological symptoms and long COVID.

Extending the Near Infrared Emission Range of Indium Phosphide Quantum Dots for Multiplexed In Vivo Imaging

This paper develops InP quantum dots with tunable NIR emission for in vivo imaging, overcoming synthesis challenges and demonstrating multiplexed lymph node imaging in mice.

Nuku, a family of primate retrogenes derived from KU70

The paper identifies and analyzes a family of primate retrogenes derived from KU70, showing evidence of functional divergence and positive selection in NUKU2.

Association between toothbrushing and non-alcoholic fatty liver disease

This study finds that higher toothbrushing frequency is inversely associated with non-alcoholic fatty liver disease (NAFLD) in Korean adults, particularly in smokers and diabetics.

Characterization of a novel gene, srpA, conferring resistance to streptogramin A, pleuromutilins, and lincosamides in Streptococcus suis

This study identifies a novel gene, srpA, in Streptococcus suis that confers resistance to multiple ribosome-targeting antibiotics by altering ribosome binding.

Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities

The paper identifies new RAS effector pathways and synthetic lethal interactions in lung adenocarcinoma using proteomic and genetic screening.

Differential risk of incident cancer in patients with heart failure: A nationwide population-based cohort study

This study finds that patients with heart failure have a higher risk of developing cancer compared to the general population, with increased risk observed across multiple cancer types.

JNK-IN-8, a c-Jun N-terminal kinase inhibitor, improves functional recovery through suppressing neuroinflammation in ischemic stroke

This study shows JNK-IN-8 improves functional recovery in ischemic stroke by reducing neuroinflammation through the JNK/NF-κB pathway.

Contribution of mobile elements to the uniqueness of human genome with more than 15,000 human-specific insertions

The paper identifies 15,463 human-specific mobile elements (HS-MEs) contributing to genome size increase and gene regulation, expanding prior knowledge by over 8,000 elements.

Multiple reference genome sequences of hot pepper reveal the massive evolution of plant disease resistance genes by retroduplication

The paper reports multiple pepper genomes and finds that retroduplication via LTR-retrotransposons drives expansion of disease resistance genes in plants.