Author

J. R. Kratz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

A. A. Rao· 2 shared A. J. Combes· 2 shared A. Shen· 2 shared D. M. Jablons· 2 shared J. Tsui· 2 shared J. Z. Li· 2 shared M. F. Krummel· 2 shared V. Chan· 2 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

A. A. Rao

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Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

L. Hysenaj, S. Little, K. R. Kulhanek, O. Gbenedio, L. Rodriguez, A. Shen, J.-C. Lone, L. C. Lupin-Jimenez, L. Bonser, N. K. Serwas, K. Bahl, E. Mick, J. Z. Li, V. Ding, S. Matsumoto, , J. P. Roose

The paper identifies TSPAN8 as a novel mediator of SARS-CoV-2 infection in lung organoids, showing its correlation with infection rates and susceptibility to blocking antibodies.

bioRxiv · Jun 1, 2021 · PreprintMicrobiology

Multiomic Characterization of Stage I Lung Adenocarcinoma Reveals Distinct Genetic and Immunologic Features of Recurrent Disease

J. R. Kratz, J. Z. Li, J. Tsui, J. C. Lee, V. W. Ding, A. A. Rao, M. J. Mann, V. Chan, A. R. Combes, M. F. Krummel, D. M. Jablons

This study identifies distinct genetic and immunologic features of recurrent stage I lung adenocarcinoma using multiomic profiling and single-cell RNA-seq.

bioRxiv · May 20, 2021 · PreprintCancer Biology

A Pan-Cancer Census of Dominant Tumor Immune Archetypes

A. J. Combes, B. Samad, J. Tsui, N. W. Chew, P. Yan, G. C. Reeder, D. Kushnoor, A. Shen, B. Davidson, A. J. Barczac, M. Adkisson, A. Edwards, M. Naser, K. C. Barry, T. Courau, , M. F. Krummel

The paper identifies dominant immune system archetypes across 364 tumors from 12 cancer types using flow cytometry and transcriptomic data, linking them to tumor biology classifications.

bioRxiv · Apr 26, 2021 · PreprintImmunology

Heterogeneity and targeted therapy-induced adaptations in lung cancer revealed by longitudinal single-cell RNA sequencing

A. Maynard, C. E. McCoach, J. K. Rotow, L. Harris, F. Haderk, L. D. Kerr, E. A. Yu, E. L. Schenk, W. Tan, A. Zee, M. Tan, P. Gui, T. Lea, W. Wu, A. Urisman, , T. G. Bivona

This study uses longitudinal single-cell RNA sequencing to reveal therapy-induced adaptations in lung cancer, identifying cell state transitions and pathways associated with treatment response and resistance.

bioRxiv · Dec 8, 2019 · PreprintCancer Biology