Author

L. Hysenaj

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Sil· 2 shared C. R. Langelier· 2 shared J. P. Roose· 2 shared L. Rodriguez· 2 shared M. Ott· 2 shared A. A. Rao· 1 shared A. J. Combes· 1 shared A. Shen· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersImmunology

A. Sil

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Immediate myeloid depot for SARS-CoV-2 in the human lung

M. Magnen, R. You, A. A. Rao, R. T. Davis, L. Rodriguez, C. R. Simoneau, L. Hysenaj, K. H. Hu, The UCSF COMET Consortium, C. Love, P. G. Woodruff, D. J. Erle, C. M. Hendrickson, C. S. Calfee, M. A. Matthay, , M. R. Looney

The paper investigates early SARS-CoV-2 infection in human lung myeloid cells, finding rapid viral tropism, ACE2 dependence, and poor interferon induction, suggesting a myeloid depot for viral persistence.

bioRxiv · Apr 28, 2022Immunology

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

L. Hysenaj, S. Little, K. R. Kulhanek, O. Gbenedio, L. Rodriguez, A. Shen, J.-C. Lone, L. C. Lupin-Jimenez, L. Bonser, N. K. Serwas, K. Bahl, E. Mick, J. Z. Li, V. Ding, S. Matsumoto, , J. P. Roose

The paper identifies TSPAN8 as a novel mediator of SARS-CoV-2 infection in lung organoids, showing its correlation with infection rates and susceptibility to blocking antibodies.

bioRxiv · Jun 1, 2021 · PreprintMicrobiology

CD150-dependent hematopoietic stem cells sensing of Brucella instructs myeloid commitment

L. Hysenaj, B. de Laval, V. Arce-Gorvel, M. Bosilkovski, G. Gonzalez, G. Debroas, M. Sieweke, S. SARRAZIN, J.- P. Gorvel

The paper shows HSC directly sense Brucella abortus via CD150 and Omp25, leading to myeloid commitment and early immune response.

bioRxiv · Mar 31, 2021 · PreprintImmunology