Author

S. Little

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Combes· 1 shared A. J. Helmstetter· 1 shared A. Oswal· 1 shared A. Sharma· 1 shared A. Shen· 1 shared A. Sil· 1 shared B. Abdi-Sargezeh· 1 shared C. R. Langelier· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. J. Combes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Predicting Long and Short Duration Beta Bursts from Subthalamic Nucleus Local Field Potential Activity in Parkinson's Disease

B. Abdi-Sargezeh, S. Shirani, A. Sharma, P. Starr, S. Little, A. Oswal

This study develops a deep learning pipeline to predict long and short duration beta bursts from subthalamic nucleus LFP recordings in Parkinson's disease patients, achieving 87% and 85.2% accuracy.

bioRxiv · Sep 22, 2023 · PreprintBioengineering

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

L. Hysenaj, S. Little, K. R. Kulhanek, O. Gbenedio, L. Rodriguez, A. Shen, J.-C. Lone, L. C. Lupin-Jimenez, L. Bonser, N. K. Serwas, K. Bahl, E. Mick, J. Z. Li, V. Ding, S. Matsumoto, , J. P. Roose

The paper identifies TSPAN8 as a novel mediator of SARS-CoV-2 infection in lung organoids, showing its correlation with infection rates and susceptibility to blocking antibodies.

bioRxiv · Jun 1, 2021 · PreprintMicrobiology

Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques

J. Petrovic, Y. Zhou, M. Fasolino, N. Goldman, G. Schwartz, M. Mumbach, S. Nguyen, K. Rome, Y. Sela, Z. Zapataro, S. Blacklow, M. Kruhlak, J. Aster, J. Shi, E. Joyce, , R. B. Faryabi

bioRxiv · Jan 22, 2019Cancer Biology

Phylogenomics of the major tropical plant family Annonaceae using targeted enrichment of nuclear genes

T. L. P. Couvreur, A. J. Helmstetter, E. E. Koenen, K. Bethume, R. D. Brandao, S. Little, H. Sauquet, R. H. J. Erkens

This study uses targeted nuclear gene sequencing to reconstruct phylogenetic relationships in Annonaceae, confirming previous chloroplast studies and identifying new relationships and a new tribe.

bioRxiv · Oct 11, 2018Evolutionary Biology