Author

J. R. Peterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. L. BURRELL· 2 shared J. M. Kollman· 2 shared M. C. Johnson· 2 shared A. Andrews· 1 shared A. Beatty· 1 shared C. Nie· 1 shared D. Fernandez-Justel· 1 shared E. Nicolas· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

A. L. BURRELL

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Author profile →

3 papers

Recent·Most cited

IMPDH1 retinal variants control filament architecture to tune allosteric regulation

A. L. BURRELL, C. Nie, M. Said, J. C. Simonet, D. Fernandez-Justel, M. C. Johnson, J. Quispe, R. M. Buey, J. R. Peterson, J. M. Kollman

The paper shows IMPDH1 retinal variants form different filaments that affect GTP regulation, with disease mutations disrupting or not affecting this regulation.

bioRxiv · Aug 3, 2021Biochemistry

Conjugated linolenic fatty acids trigger ferroptosis in triple-negative breast cancer

A. Beatty, T. Singh, Y. Y. Tyurina, E. Nicolas, K. Maslar, Y. Zhou, K. Q. Cai, Y. Tan, S. Doll, M. Conrad, H. Bayır, V. E. Kagan, U. Rennefahrt, J. R. Peterson

This study identifies conjugated linolenic acids as ferroptosis inducers in triple-negative breast cancer and shows their anti-tumor effects in a xenograft model.

bioRxiv · Feb 20, 2019 · PreprintCancer Biology

IMPDH polymers accommodate both catalytically active and inactive conformations

S. Anthony, A. L. Burrell, M. C. Johnson, K. C. Duong-Ly, K. Yin-Ming, P. Michener, A. Andrews, J. M. Kollman, J. R. Peterson

The paper investigates IMPDH polymerization and finds that polymerized and non-assembled forms have comparable catalytic activity, with substrate and nucleotide availability affecting filament conformation.

bioRxiv · Jun 19, 2017Biochemistry