Author

A. Andrews

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

M. C. Johnson· 2 shared Y.-M. Kuo· 2 shared A. Carrer· 1 shared A. Farria· 1 shared A. L. Burrell· 1 shared A. Pribisova· 1 shared B. C. Capell· 1 shared C. Demetriadou· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

M. C. Johnson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The carnitine shuttle links mitochondrial metabolism to histone acetylation and lipogenesis

L. T. Izzo, S. Trefely, C. Demetriadou, J. Drummond, T. Mizukami, N. Kuprasertkul, A. Farria, P. Nguyen, L. Reich, J. Shaffer, H. Affronti, A. Carrer, A. Andrews, B. C. Capell, N. W. Snyder, K. E. Wellen

This study identifies the carnitine shuttle and CrAT as a pathway for mitochondrial-to-cytosolic acetyl-CoA transfer, independent of ACLY, in cancer cells.

bioRxiv · Sep 24, 2022 · PreprintCell Biology

Spatially distributed infection increases viral load in a computational model of SARS-CoV-2 lung infection

M. E. Moses, S. Hofmeyr, J. L. Cannon, A. Andrews, R. Gridley, M. Hinga, K. Leyba, A. Pribisova, V. Surjadidjaja, H. Tasnim, S. Forrest

This paper develops a computational model of SARS-CoV-2 lung infection that shows spatially distributed infections increase viral load and demonstrates how T cell response timing affects viral persistence.

bioRxiv · May 19, 2021Immunology

Two factor authorization: Asf1 mediates crosstalk between H3 K14 and K56 acetylation

J. M. Cote, Y.-M. Kuo, R. A. Henry, H. Scherman, A. Andrews

The paper investigates how acetylation crosstalk between H3K14 and H3K56 influences Rtt109-Vps75 selectivity, showing Asf1 mediates this interaction.

bioRxiv · Aug 9, 2018Biochemistry

T Cell Activation Triggers Reversible Inosine-5’-Monophosphate Dehydrogenase Assembly

K. Duong-Ly, Y.-M. Kuo, M. C. Johnson, J. Kollman, J. Soboloff, G. Rall, A. Andrews, J. Peterson

This study shows T cell activation leads to reversible IMPDH assembly into filaments, regulated by mTOR and STIM1, with implications for guanine nucleotide biosynthesis and T cell proliferation.

bioRxiv · May 16, 2018Immunology

IMPDH polymers accommodate both catalytically active and inactive conformations

S. Anthony, A. L. Burrell, M. C. Johnson, K. C. Duong-Ly, K. Yin-Ming, P. Michener, A. Andrews, J. M. Kollman, J. R. Peterson

The paper investigates IMPDH polymerization and finds that polymerized and non-assembled forms have comparable catalytic activity, with substrate and nucleotide availability affecting filament conformation.

bioRxiv · Jun 19, 2017Biochemistry