Author

V. E. Kagan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. A. Sims· 1 shared A. Beatty· 1 shared A. U. Gurkar· 1 shared E. Nicolas· 1 shared E. Siefken· 1 shared H. Bayir· 1 shared H. Bayır· 1 shared H. L. Pepper· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. A. Sims

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Persistent DNA damage rewires lipid metabolism and promotes histone hyperacetylation via MYS-1/Tip60.

S. Hamsanathan, T. Anthonymuthu, S. J. Mullet, S. Han, H. Shinglot, E. Siefken, A. A. Sims, P. Sen, H. L. Pepper, S. G. Wendell, N. W. Snyder, H. Bayir, V. E. Kagan, A. U. Gurkar

This study shows persistent DNA damage alters lipid metabolism and histone acetylation via MYS-1/Tip60, leading to immune-like responses and age-related decline.

bioRxiv · Jun 24, 2021Cell Biology

Activation of Cytochrome C Peroxidase Function Through Coordinated Foldon Loop Dynamics upon Interaction with Anionic Lipids

M. Li, W. Sun, V. A. Tyurin, M. DeLucia, J. Ahn, V. E. Kagan, P. C. A. van der Wel

This study investigates how cardiolipin and phosphatidylglycerol lipids induce structural and dynamic changes in cytochrome c, affecting its peroxidase activity during mitochondrial apoptosis.

bioRxiv · Feb 24, 2021Biophysics

Conjugated linolenic fatty acids trigger ferroptosis in triple-negative breast cancer

A. Beatty, T. Singh, Y. Y. Tyurina, E. Nicolas, K. Maslar, Y. Zhou, K. Q. Cai, Y. Tan, S. Doll, M. Conrad, H. Bayır, V. E. Kagan, U. Rennefahrt, J. R. Peterson

This study identifies conjugated linolenic acids as ferroptosis inducers in triple-negative breast cancer and shows their anti-tumor effects in a xenograft model.

bioRxiv · Feb 20, 2019 · PreprintCancer Biology