Author

M. J. Sweet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:ecology & biodiversity· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Burian· 1 shared A. Khromykh· 1 shared A. S. Amiss· 1 shared A. S. Yap· 1 shared B. J. Arachchige· 1 shared B. J. Currie· 1 shared B. Matthews· 1 shared C. Mauvisseau· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEcology

A. Burian

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia.

K. Duszyc, J. von Pein, D. Ramnath, D. Currin-Ross, S. Verma, F. Lim, M. J. Sweet, K. Schroder, A. S. Yap

The paper shows that apical extrusion prevents apoptosis from triggering inflammation in epithelia by eliminating apoptotic cells before they activate an IL-8-driven inflammatory response.

bioRxiv · Feb 12, 2023Cell Biology

Oxysterols drive inflammation via GPR183 during influenza virus and SARS-CoV-2 infection

C. X. Foo, S. Bartlett, K. Y. Chew, M. D. Ngo, H. Bielefeldt-Ohmann, B. J. Arachchige, B. Matthews, S. Reed, R. Wang, M. J. Sweet, L. Burr, J. E. Sinclair, R. Parry, A. Khromykh, K. R. Short, , K. Ronacher

This study identifies oxysterols and GPR183 as drivers of inflammation in the lung during influenza and SARS-CoV-2 infections, showing that targeting GPR183 reduces inflammation and disease severity.

bioRxiv · Jun 14, 2022Immunology

Modified defence peptides from horseshoe crab target and kill bacteria inside host cells

A. S. Amiss, J. B. von Pein, J. R. Webb, N. D. Condon, P. J. Harvey, M.-D. Phan, M. A. Schembri, B. J. Currie, M. J. Sweet, D. J. Craik, R. Kapetanovic, S. T. Henriques, N. Lawrence

This study identifies modified antimicrobial peptides from horseshoe crabs that effectively kill bacteria, including UPEC, both extracellularly and intracellularly, with reduced toxicity to mammalian cells.

bioRxiv · Jun 27, 2021Microbiology

Development and application of eDNA-based tools for the conservation of white-clawed crayfish

C. R. Troth, A. Burian, Q. Mauvisseau, M. Bulling, J. Nightingale, C. Mauvisseau, M. J. Sweet

The paper develops an eDNA assay for white-clawed crayfish and evaluates its performance in detecting species presence, interactions with pathogens and invasive species, and optimal sampling methods.

bioRxiv · Feb 18, 2020Ecology