J. Ren

This paper identifies CR3022 as a monoclonal antibody that neutralizes SARS-CoV-2 by destroying its prefusion Spike conformation, suggesting therapeutic potential.

This paper validates a method to quantify aristolochic acid DNA adducts in human tissues and applies it to hepatocellular carcinoma samples, finding a low prevalence of adducts.

The paper identifies a lipid-binding pocket in the SARS-CoV-2 Spike that stabilizes the prefusion trimer and shields neutralizing epitopes, suggesting it as a potential drug target.

The paper identifies public antibody clones in the human repertoire, including virus-neutralizing and anti-PD1 clones, and introduces a tool for analyzing Rep-seq data.

This paper identifies an antibody, EY6A, from a convalescent patient that neutralizes SARS-CoV-2 and cross-reacts with SARS-CoV-1 by binding a conserved epitope on the Spike protein.

This study shows mitophagy protects beta cells from inflammatory damage in diabetes by reducing mitochondrial dysfunction and cell death.

This study quantifies hair graying and its reversal in humans, linking it to stress and showing proteomic and computational evidence of reversibility.

The paper develops a tandem tension sensor to measure integrin molecular tensions in live cells and finds that these tensions decrease with increasing substrate rigidity.

The study shows that millet-based supplements improve gut microbiota diversity in undernourished pigs more effectively than corn-based supplements.

The paper uses biosensors to analyze GEF-GTPase interactions in living cells and identifies functional relationships that regulate cell edge dynamics.

This study shows KGF induces podosome formation in HIOECs through integrin-Erk1/2 signaling, enhancing epithelial adhesion and rete peg elongation.

This study shows C. elegans avoids Pseudomonas aeruginosa by detecting its nitric oxide, with TRX-1 modulating the sensory response through redox sensing.

This study identifies SmWRKY1 as a positive regulator of tanshinone biosynthesis in Salvia miltiorrhiza by enhancing MEP pathway gene expression.