Author

J. Schwarze

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Bush· 1 shared A. Custovic· 1 shared A. J. Simpson· 1 shared A. Rossi· 1 shared A. Rostron· 1 shared A. S. Mirchandani· 1 shared A. Zhang· 1 shared B. Marsland· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. Bush

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence

A. S. Mirchandani, S. J. Jenkins, C. C. Bain, H. Lawson, P. Coelho, F. Murphy, D. Griffith, A. Zhang, M. A. Sanchez-Garcia, L. Reyes, T. Morrison, S. Arienti, P. Sadiku, E. Watts, R. Dickinson, , S. Walmsley

This study shows hypoxia suppresses type I interferon signaling in ALI, leading to monocytopenia and unchecked inflammation, which can be mitigated by CSF1 administration.

bioRxiv · Mar 11, 2022 · PreprintCell Biology

Metabolic regulation by prostaglandin E2 impairs lung group 2 innate lymphoid cell responses

C. Robb, Y. Zhou, J. Felton, B. Zhang, M. Goepp, P. Jheeta, D. Smyth, R. Breyer, S. Narumiya, H. McSorley, R. Maizels, J. Schwarze, A. Rossi, C. Yao

This study identifies that PGE2-EP2 signaling suppresses lung ILC2 responses and eosinophilic inflammation, while EP4 agonism restricts these responses, offering potential therapeutic targets for asthma and NERD.

bioRxiv · Dec 23, 2021Immunology

Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media.

L. Broadbent, S. Manzoor, M. Zarcone, J. Barabas, M. Shields, S. Saglani, C. M. Lloyd, A. Bush, A. Custovic, P. Ghazal, M. Gore, B. Marsland, G. Roberts, J. Schwarze, S. Turner, U. F. Power

This study compares two commercial media for culturing primary nasal epithelial cells and evaluates their impact on cell morphology, physiology, and RSV infection outcomes.

bioRxiv · Jan 13, 2020Cell Biology