Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR
S.-B. Amos, T. Schwarz, J. Shih, B. Cossins, T. Baker, R. Taylor, R. Konrat, M. Sansom
This study uses multiscale simulations and NMR to reveal structural changes in α-synuclein bound to lipid bilayers, providing insights into its role in Parkinson's disease.
bioRxiv · Jun 18, 2020Biophysics