Author

J. Smazynski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. J. Lum· 2 shared M. K. Kilgour· 2 shared R. J. DeBerardinis· 2 shared S. Keyes· 2 shared S. MacPherson· 2 shared A. Devlieger· 1 shared B. Allard· 1 shared B. H. Nelson· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

J. J. Lum

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2 papers

Recent·Most cited

Clinically-relevant T cell expansion protocols activate distinct cellular metabolic programs and phenotypes

S. MacPherson, S. Keyes, M. K. Kilgour, J. Smazynski, J. Sudderth, T. Turcotte, A. Devlieger, J. Yu, K. S. Huggler, J. R. Cantor, R. J. DeBerardinis, C. Siatskas, J. J. Lum

The paper compares five T cell expansion protocols and finds they induce distinct metabolic programs and phenotypes, with some conditions impairing T cell function despite metabolic adaptation.

bioRxiv · Aug 24, 2021Immunology

1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer

M. K. Kilgour, S. MacPherson, L. Zacharias, S. Keyes, B. Pauly, B. Allard, J. Smazynski, P. H. Watson, J. Stagg, B. H. Nelson, R. J. DeBerardinis, P. T. Hamilton, J. J. Lum

This study identifies 1-methylnicotinamide (MNA) as an immune regulatory metabolite in high-grade serous ovarian cancer, showing its role in modulating T cell function through non-cell autonomous mechanisms.

bioRxiv · May 5, 2020Immunology