Author

J. Sudderth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell signaling & trafficking· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

R. J. DeBerardinis· 3 shared L. Cai· 2 shared A. B. Aurora· 1 shared A. Bagrodia· 1 shared A. Devlieger· 1 shared A. Leach· 1 shared A. M. Poole· 1 shared B. Brooks· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

R. J. DeBerardinis

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Author profile →

3 papers

Recent·Most cited

Mitochondrial metabolism in primary and metastatic human kidney cancers

D. Bezwada, R. J. DeBerardinis, N. P. Lesner, B. Brooks, H. S. Vu, Z. Wu, L. Cai, S. Kasitinon, S. Kelekar, F. Cai, A. B. Aurora, M. Patrick, A. Leach, R. Ghandour, Y. Zhang, , V. Margulis

This study investigates mitochondrial metabolism in kidney cancers, finding that primary tumors have suppressed mitochondrial function while metastases show enhanced TCA cycle labeling.

bioRxiv · Feb 6, 2023Cancer Biology

Clinically-relevant T cell expansion protocols activate distinct cellular metabolic programs and phenotypes

S. MacPherson, S. Keyes, M. K. Kilgour, J. Smazynski, J. Sudderth, T. Turcotte, A. Devlieger, J. Yu, K. S. Huggler, J. R. Cantor, R. J. DeBerardinis, C. Siatskas, J. J. Lum

The paper compares five T cell expansion protocols and finds they induce distinct metabolic programs and phenotypes, with some conditions impairing T cell function despite metabolic adaptation.

bioRxiv · Aug 24, 2021Immunology

METABOLIC DIVERSITY IN HUMAN NON-SMALL CELL LUNG CANCER CELLS

P.-H. CHEN, L. Cai, C. Yang, J. Kim, B. Faubert, L. Boroughs, B. Ko, J. Sudderth, E. A. McMillan, L. Girard, M. Peyton, K. Huffman, M. D. Shields, D. Shames, H. S. Kim, , R. J. DeBerardinis

The paper quantifies metabolic features in NSCLC cell lines to explore associations between metabolism and other cell-autonomous processes.

bioRxiv · Mar 11, 2019Cancer Biology