Author

J. Soboloff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Andrews· 1 shared A. C. Lilly· 1 shared A. Deneka· 1 shared A. Efimov· 1 shared A. Klochkova· 1 shared A. M. Charles Solomon· 1 shared A. Sipman· 1 shared A. Surumbayeva· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Andrews

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2 papers

Recent·Most cited

Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6).

C. Ogier, A. M. Charles Solomon, Z. Lu, L. Recoules, A. Klochkova, L. Gabitova-Cornell, B. Bayarmagnai, D. Restifo, A. Surumbayeva, D. B. Vendramini-Costa, A. Deneka, R. Francescone, A. C. Lilly, A. Sipman, J. C. Gardiner, , I. Astsaturov

This study identifies ANO6-mediated trogocytosis as a mechanism by which CAFs transfer lipids to PDAC cells, promoting tumor growth and immune suppression.

bioRxiv · Sep 15, 2023 · PreprintCancer Biology

T Cell Activation Triggers Reversible Inosine-5’-Monophosphate Dehydrogenase Assembly

K. Duong-Ly, Y.-M. Kuo, M. C. Johnson, J. Kollman, J. Soboloff, G. Rall, A. Andrews, J. Peterson

This study shows T cell activation leads to reversible IMPDH assembly into filaments, regulated by mTOR and STIM1, with implications for guanine nucleotide biosynthesis and T cell proliferation.

bioRxiv · May 16, 2018Immunology