Author

J. T. Brenna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

K. S. D. Kothapalli· 2 shared P. Lawrence· 2 shared A. Narala· 1 shared A. S. Flecker· 1 shared B. Dong· 1 shared C. Kocherlakota· 1 shared C. W. Twining· 1 shared D. A. Sheeter· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCancer Biology

K. S. D. Kothapalli

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unsaturated fatty acid synthesis is associated with poor prognosis and differentially regulated by MYCN and tumor suppressor microRNAs in neuroblastoma

D. A. Sheeter, S. Garza, H. G. Park, N. R. Badi, E. Espinosa, K. S. D. Kothapalli, J. T. Brenna, J. T. Powers

This study identifies unsaturated fatty acid synthesis (UFAS) as a factor associated with poor neuroblastoma prognosis, showing its regulation by MYCN and tumor suppressor microRNAs.

bioRxiv · Apr 20, 2023 · PreprintCancer Biology

Evaluation of the Efficacy of Omega-3 Fatty Acids Formulations in the Lipopolysaccharide-Induced Acute Lung Inflammation Rat Model

C. Kocherlakota, N. Banda, A. Narala, S. Akula, K. S. D. Kothapalli, J. T. Brenna

This study evaluates the efficacy of inhaled omega-3 fatty acid formulations in reducing LPS-induced acute lung inflammation in rats, finding that ethyl ester forms were most effective.

bioRxiv · Nov 23, 2021 · PreprintPhysiology

LRH-1 NUTRIGENOMICS: The Provision of Lauric Acid Results in the Endogenous Production of the Liver Receptor Homolog-1 Ligand, Dilauroylphosphatidylcholine, and LRH-1 Transactivation

K. C. Klatt, S. Zhang, O. V. Malysheva, Z. Sun, B. Dong, J. T. Brenna, D. D. Moore, M. S. Roberson, M. A. Caudill

This study shows that lauric acid intake leads to endogenous production of DLPC, an LRH-1 ligand, and enhances LRH-1 transcriptional activity in multiple tissues.

bioRxiv · Feb 1, 2021 · PreprintPhysiology

Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids

S. C. Di Rienzi, J. Jacobson, E. A. Kennedy, M. E. Bell, Q. Shi, J. L. Waters, P. Lawrence, J. T. Brenna, R. A. Britton, J. Walter, R. E. Ley

This study shows that small intestinal lactobacilli can resist the toxicity of soybean oil fatty acids through environmental protection and evolutionary adaptation.

bioRxiv · Mar 15, 2018Microbiology

Taking the short- or long-chain route: conversion efficiency of alpha linolenic acid to long-chain omega-3 fatty acids in aerial insectivore chicks

C. W. Twining, P. Lawrence, D. W. Winkler, A. S. Flecker, J. T. Brenna

This study shows Tree Swallows can convert ALA to LCPUFA but face limitations due to low ALA availability in terrestrial foods, highlighting the ecological importance of LCPUFA-rich aquatic insects.

bioRxiv · Jun 26, 2017Ecology