Author

O. V. Malysheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. A. Caudill· 2 shared B. Dong· 1 shared C. Metallo· 1 shared D. D. Moore· 1 shared J. L. Fiddler· 1 shared J. T. Brenna· 1 shared K. C. Klatt· 1 shared K. E. Heyden· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

M. A. Caudill

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2 papers

Recent·Most cited

Reduced methionine synthase (Mtr) expression creates a functional vitamin B12 deficiency that leads to uracil accumulation in mouse mitochondrial DNA

K. E. Heyden, J. L. Fiddler, Y. Xiu, O. V. Malysheva, M. K. Handzlik, W. N. Phinney, L. Stiles, S. S. Stabler, C. Metallo, M. A. Caudill, M. S. Field

This study shows that reduced Mtr expression causes B12 deficiency, leading to uracil accumulation in mtDNA and impaired mitochondrial function in mice.

bioRxiv · Aug 29, 2022 · PreprintBiochemistry

LRH-1 NUTRIGENOMICS: The Provision of Lauric Acid Results in the Endogenous Production of the Liver Receptor Homolog-1 Ligand, Dilauroylphosphatidylcholine, and LRH-1 Transactivation

K. C. Klatt, S. Zhang, O. V. Malysheva, Z. Sun, B. Dong, J. T. Brenna, D. D. Moore, M. S. Roberson, M. A. Caudill

This study shows that lauric acid intake leads to endogenous production of DLPC, an LRH-1 ligand, and enhances LRH-1 transcriptional activity in multiple tissues.

bioRxiv · Feb 1, 2021 · PreprintPhysiology