Author

J. T. Harty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Goeken· 1 shared A. J. Klingelhutz· 1 shared B. M. Ripley· 1 shared B. Manicassamy· 1 shared B. Poudel· 1 shared C. Marques-da-Silva· 1 shared C. S. Stipp· 1 shared D. E. Kyle· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Goeken

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintDec 27, 2022

ISG15-modification of the Arp2/3 complex restricts pathogen spread

Y. Zhang, B. M. Ripley, W. Ouyang…·L. Radoshevich

This study shows ISG15 modifies the Arp2/3 complex to restrict pathogen spread by slowing actin filament formation and stabilizing structures, but pathogens like Listeria exploit dysregulated ISGylation to enhance spread.

DOI 10.1101/2022.12.27.522022

mouseproteomics

ImmunologybioRxivPreprintJan 28, 2021

Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver

C. Marques-da-Silva, B. Poudel, R. P. Baptista…·S. P. Kurup

This study shows that limited Caspase-1 cleavage in hepatocytes reduces pyroptosis and cytokine maturation, impairing malaria control, and that enhancing ASC expression improves immune response.

DOI 10.1101/2021.01.28.427517

mousebulk RNA-seq