Author

J. T. Tometich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Bhattacharjee· 2 shared A. E. Overacre-Delgoffe· 2 shared A. H. P. Burr· 2 shared T. W. Hand· 2 shared A. H. Burr· 1 shared A. R. Cillo· 1 shared A. T. Rai· 1 shared B. R. Huckestein· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Bhattacharjee

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Author profile →

3 papers

Recent·Most cited

Stability and heterogeneity in the anti-microbiota reactivity of human milk-derived Immunoglobulin A

T. W. Hand, C. Johnson-Hence, K. P. Gopalakrishna, D. Bodkin, K. E. Coffey, A. H. P. Burr, S. Rahman, A. T. Rai, D. A. Abbott, Y. A. Sosa, J. T. Tometich, J. Das

This study examines the reactivity of breast milk-derived IgA against the infant microbiota, finding inter-donor heterogeneity and intra-donor stability in anti-bacterial IgA responses.

bioRxiv · Mar 16, 2023 · PreprintImmunology

Microbiome-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer.

A. E. Overacre-Delgoffe, A. R. Cillo, H. J. Bumgarner, A. H. Burr, J. T. Tometich, A. Bhattacharjee, T. C. Bruno, D. A. Vignali, T. Hand

The paper shows that introducing an immunogenic commensal bacteria modifies the microbiome to enhance anti-tumor immunity in colorectal cancer by promoting tertiary lymphoid structures and T follicular helper cell activity.

bioRxiv · Jan 27, 2021 · PreprintImmunology

Enteropathy-induced regulatory T cells inhibit intestinal CD4+ T cell responses against oral vaccines

A. Bhattacharjee, A. H. P. Burr, A. E. Overacre-Delgoffe, J. T. Tometich, D. Yang, B. R. Huckestein, J. L. Linehan, S. P. Spencer, J. A. Hall, O. J. Harrison, D. Morais da Fonseca, E. B. Norton, Y. Belkaid, T. W. Hand

This study shows that EED-induced Tregs suppress intestinal CD4+ T cell responses to oral vaccines, but not lymph node responses, and worsen stunting when depleted.

bioRxiv · Jun 3, 2020 · PreprintImmunology