Author

O. J. Harrison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 6 Research Focus:cell type annotation· 5 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Y. Belkaid· 3 shared A. I. Lim· 2 shared M. J. Dufort· 2 shared A. Bhattacharjee· 1 shared A. C. Wells· 1 shared A. E. Overacre-Delgoffe· 1 shared A. H. P. Burr· 1 shared A. L. Byrd· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersImmunology

Y. Belkaid

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

B cell alpha(v) integrin regulates tissue specialization and clonal expansion of lung germinal center and memory B cells after viral infection.

A. Montiel-Armendariz, K. Roe, J. Lagos-Orellana, L. V. Martinez-Castro, M. J. Dufort, O. J. Harrison, A. Lacy-Hulbert, M. Acharya

This study shows that B cell v integrin limits GC activity and memory B cell expansion in the lung after IAV infection, suggesting it as a target for improving mucosal vaccines.

bioRxiv · Apr 3, 2024Immunology

The neuroimmune CGRP-RAMP1 axis tunes cutaneous adaptive immunity to the microbiota

W. Kulalert, A. C. Wells, V. M. Link, A. I. Lim, N. Bouladoux, M. Nagai, O. J. Harrison, O. Kamenyeva, J. Kabat, M. Enamorado, I. Chiu, Y. Belkaid

This study identifies a neuroimmune CGRP-RAMP1 axis that modulates cutaneous adaptive immunity to the microbiota by constraining Type 17 responses and limiting T cell activation.

bioRxiv · Dec 26, 2023 · PreprintImmunology

Antigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers

S. Verma, M. J. Dufort, T. M. Olsen, J. C. Labuda, S. Kimmel, S. Scharffenberger, A. McGuire, O. J. Harrison

This study identifies SFB-specific B cell responses using phage display and tetramers, revealing compartmentalized activation and isotype gradients in the gut.

bioRxiv · Oct 13, 2023Immunology

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

C.-P. Hackstein, D. Costigan, L. Drexhage, C. Pearson, S. Bullers, N. Ilott, H. D. Akther, Y. Gu, M. E. B. FitzPatrick, O. J. Harrison, L. C. Garner, E. H. Mann, S. Pandey, M. Friedrich, N. M. Provine, , E. E. Thornton

The paper identifies a conserved population of MHC-II restricted, innate-like T cells in the gut of humans and mice that react to commensals and are implicated in colitis.

bioRxiv · Sep 26, 2022 · PreprintImmunology

Maternal infection promotes offspring tissue-specific immune fitness

A. I. Lim, T. McFadden, V. Link, S.-J. Han, R.-M. Karlsson, A. Stacy, T. K. Farley, O. J. Harrison, H.-Y. Shih, H. A. Cameron, Y. Belkaid

Maternal infection during pregnancy leads to tissue-specific immune changes in offspring through IL-6-induced epigenetic modifications in intestinal epithelial cells.

bioRxiv · Jan 13, 2021 · PreprintImmunology

Enteropathy-induced regulatory T cells inhibit intestinal CD4+ T cell responses against oral vaccines

A. Bhattacharjee, A. H. P. Burr, A. E. Overacre-Delgoffe, J. T. Tometich, D. Yang, B. R. Huckestein, J. L. Linehan, S. P. Spencer, J. A. Hall, O. J. Harrison, D. Morais da Fonseca, E. B. Norton, Y. Belkaid, T. W. Hand

This study shows that EED-induced Tregs suppress intestinal CD4+ T cell responses to oral vaccines, but not lymph node responses, and worsen stunting when depleted.

bioRxiv · Jun 3, 2020 · PreprintImmunology

Stability and dynamics of the human gut microbiome and its association with systemic immune traits

A. L. Byrd, M. Liu, K. E. Fujimura, S. Lyalina, D. R. Nagarkar, B. Charbit, E. Patin, O. J. Harrison, L. Quintana-Murci, D. Duffy, M. L. Albert, The Milieu Interieur Consortium

The paper analyzes gut microbiome data from 946 donors to show age-related changes in bacterial profiles and links them to immune traits, supporting personalized microbial therapeutics.

bioRxiv · Jan 17, 2020Microbiology