Author

A. R. Cillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

T. C. Bruno· 5 shared D. A. Vignali· 4 shared A. Somasundaram· 3 shared C. Lampenfeld· 3 shared A. Morris· 2 shared A. Ray· 2 shared B. J. McVerry· 2 shared B. Methe· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

T. C. Bruno

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Author profile →

5 papers

Recent·Most cited

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19

S. P. Peddireddy, S. A. Rahman, A. R. Cillo, G. M. Vijay, A. Somasundaram, C. J. Workman, W. Bain, B. J. McVerry, B. Methe, J. S. Lee, P. Ray, A. Ray, T. C. Bruno, D. A. Vignali, G. D. Kitsios, , J. Das

The paper identifies antibody responses against non-canonical and endemic coronavirus antigens as predictors of favorable outcomes in severe COVID-19.

bioRxiv · Jan 24, 2022Immunology

Bifurcated monocyte states are predictive of mortality in severe COVID-19

A. R. Cillo, A. Somasundaram, F. Shan, C. Cardello, C. J. Workman, G. D. Kitsios, A. Ruffin, S. Kunning, C. Lampenfeld, S. Onkar, S. Grebinowski, G. Deshmukh, B. Methe, C. Liu, S. Nambulli, , D. A. Vignali

The paper identifies bifurcated monocyte states in severe COVID-19 patients that predict mortality, with distinct cytokine and interferon gene modules associated with survival or death.

bioRxiv · Feb 10, 2021 · PreprintImmunology

Microbiome-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer.

A. E. Overacre-Delgoffe, A. R. Cillo, H. J. Bumgarner, A. H. Burr, J. T. Tometich, A. Bhattacharjee, T. C. Bruno, D. A. Vignali, T. Hand

The paper shows that introducing an immunogenic commensal bacteria modifies the microbiome to enhance anti-tumor immunity in colorectal cancer by promoting tertiary lymphoid structures and T follicular helper cell activity.

bioRxiv · Jan 27, 2021 · PreprintImmunology

Divergent cancer etiologies drive distinct B cell signatures and tertiary lymphoid structures

A. T. Ruffin, A. R. Cillo, T. Tabib, A. Liu, S. Onkar, S. Kunning, C. Lampenfeld, I. Abecassis, Z. Qi, R. Soose, U. D. Duvvuri, S. Kim, S. Oesterreich, R. Lafyatis, R. L. Ferris, , T. C. Bruno

This study identifies distinct B cell signatures and tertiary lymphoid structures in HPV+ and HPV- HNSCC, highlighting their role in antitumor immunity.

bioRxiv · May 29, 2020 · PreprintImmunology

Systemic immune dysfunction in cancer patients driven by IL6 and IL8 induction of an inhibitory receptor module in peripheral CD8+ T cells

A. Somasundaram, A. R. Cillo, C. Lampenfeld, L. Oliveri, M. A. Velez, S. Joyce, M. J. Calderon, R. Dadey, D. Rajasundaram, D. P. Normolle, S. C. Watkins, J. G. Herman, J. M. Kirkwood, E. J. Lipson, R. L. Ferris, , D. A. A. Vignali

This study identifies a systemic immune dysfunction in cancer patients driven by IL6 and IL8, leading to CD8+ T cell dysfunction and poor prognosis.

bioRxiv · May 6, 2020 · PreprintCancer Biology