Author

J. Tait-Mulder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metabolomics· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Athineos· 2 shared D. Sumpton· 2 shared K. Blyth· 2 shared M. Pietzke· 2 shared S. Dhayade· 2 shared S. Lilla· 2 shared S. Zanivan· 2 shared A. B. Vazquez· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

D. Athineos

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Author profile →

3 papers

Recent·Most cited

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade

M. Mahmood, E. M. Liu, A. L. Shergold, E. Tolla, J. Tait-Mulder, A. H. Uribe, E. Shokry, A. L. Young, S. Lilla, M. Kim, T. Park, J. L. Manchon, C. Rodriguez-Antona, R. C. Walters, R. J. Springett, , P. A. Gammage

This study shows that mitochondrial DNA mutations in complex I genes drive aerobic glycolysis, enhancing immune checkpoint blockade response in tumors.

bioRxiv · Mar 21, 2023 · PreprintCancer Biology

Impact of formate supplementation on body weight and plasma amino acids

S. Dhayade, M. Pietzke, R. Wiesheu, J. Tait-Mulder, D. Athineos, D. Sumpton, S. B. Coffelt, K. Blyth, A. B. Vazquez

This study examines the effects of sodium formate supplementation on body weight, plasma amino acids, and gut microbiota in mice, finding significant changes in females but not males.

bioRxiv · May 4, 2020Biochemistry

Formate induces a metabolic switch in nucleotide and energy metabolism

K. Oizel, J. Tait-Mulder, J. Fernandez-de-Cossio-Diaz, M. Pietzke, H. Brunton, S. Dhayade, D. Athineos, S. Lilla, G. Rodriguez Blanco, D. Sumpton, G. M. Mackay, K. Blyth, S. Zanivan, J. Meiser, A. Vazquez

This study shows formate induces a metabolic switch increasing adenine nucleotides, glycolysis, and repressing AMPK, with implications for cancer metabolism.

bioRxiv · Aug 16, 2019Biochemistry