Author

E. Shokry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Assay:metabolomics· 4 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Nixon· 3 shared D. Sumpton· 3 shared S. Zanivan· 3 shared K. Blyth· 2 shared L. Mitchell· 2 shared S. Tardito· 2 shared A. Burton· 1 shared A. Campos· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

C. Nixon

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments

M. Gounis, A. Campos, E. Shokry, L. Mitchell, E. Dornier, N. Rooney, S. Dhayade, L. Pardo, M. Moore, D. Novo, J. Mowat, C. Jamieson, E. Kay, S. Zanivan, C. Nixon, , C. Clarke

The paper shows that breast cancer micrometastases alter metabolism to change extracellular vesicle production, creating an invasive microenvironment.

bioRxiv · May 12, 2024Cancer Biology

Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis

T. Ackermann, E. Shokry, R. Deshmukh, J. Anand, L. C. A. Galbraith, L. Mitchell, G. Rodriguez-Blanco, V. H. Villar, B. A. Sterken, C. Nixon, S. Zanivan, K. Blyth, D. Sumpton, S. Tardito

This study shows that triple-negative breast cancer cells secrete anti-ferroptotic MUFAs and rely on selenoprotein synthesis for metastasis.

bioRxiv · Jun 13, 2023Cancer Biology

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade

M. Mahmood, E. M. Liu, A. L. Shergold, E. Tolla, J. Tait-Mulder, A. H. Uribe, E. Shokry, A. L. Young, S. Lilla, M. Kim, T. Park, J. L. Manchon, C. Rodriguez-Antona, R. C. Walters, R. J. Springett, , P. A. Gammage

This study shows that mitochondrial DNA mutations in complex I genes drive aerobic glycolysis, enhancing immune checkpoint blockade response in tumors.

bioRxiv · Mar 21, 2023 · PreprintCancer Biology

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

J. Vande Voorde, A. K. Najumudeen, R. T. Steven, C. J. Nikula, A. Dexter, L. B. Zeiger, E. A. Elia, A. Nassif, A. Gonzalez-Fernandez, T. Murta, M. Gillespie, C. A. Ford, T. R. M. Lannagan, N. Vlahov, R. A. Ridgway, , O. J. Sansom

This study uses metabolomics to stratify colorectal cancer tissues and identifies adenosylhomocysteinase as a potential therapeutic target.

bioRxiv · Mar 12, 2023Cancer Biology