Author

J. V. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:CITE-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. M. O'Rourke· 2 shared L. Zhang· 2 shared R. Thokala· 2 shared Y. Yin· 2 shared Z. A. Binder· 2 shared D. Kainth· 1 shared D. Y. Zhang· 1 shared E. X. Johns· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

D. M. O'Rourke

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Locally secreted BiTEs complement CAR T cells by enhancing solid tumor killing

Y. Yin, J. Rodriguez, N. Li, R. Thokala, M. P. Nasrallah, L. Hu, L. Zhang, J. V. Zhang, D. Kainth, L. Haddad, E. X. Johns, Y. Long, H. Liang, J. Qi, X. Zhang, , D. M. O'Rourke

This study shows that BiTE-secreting T cells outperform CAR T cells in killing glioma cells in vitro and in vivo, with enhanced cytotoxicity and tumor growth delay.

bioRxiv · Jun 8, 2021 · PreprintCancer Biology

High Affinity Chimeric Antigen Receptor with Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms

R. Thokala, Z. A. Binder, Y. Yin, L. Zhang, J. V. Zhang, D. Y. Zhang, M. C. Milone, G.-L. Ming, H. Song, D. M. O'Rourke

This paper develops a CAR T cell with broad EGFR specificity to target multiple tumor clones and reduce antigen loss escape in glioblastoma.

bioRxiv · Feb 4, 2021Cancer Biology