Author

J. Zehnder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 2 Assay:electronic health records· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

T. Wiegand· 4 shared A. Bockmann· 3 shared B. H. Meier· 3 shared R. Cadalbert· 3 shared L. Lecoq· 2 shared M. E. Weber· 2 shared M.-L. Fogeron· 2 shared A. A. Malaer· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersBiophysics

T. Wiegand

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging

L. Emmanouilidis, E. Bartalucci, Y. Kan, M. Ijavi, M. E. Perez, P. Afanasyev, D. Boehringer, J. Zehnder, S. H. Parekh, M. Bonn, T. C. T. Michaels, T. Wiegand, F. H.- T. Allain

This study investigates FUS liquid droplet maturation, revealing a solid beta-sheet surface layer that forms during aging, with RNA inhibiting this process.

bioRxiv · Jun 2, 2023Biochemistry

Enkurin: A novel marker for myeloproliferative neoplasms from platelet, megakaryocyte, and whole blood specimens.

M. S. Sumanth, Y. Liu, J. Wu, L. Fechter, K. Murugesan, H. Maecker, J. Gotlib, J. Zehnder, R. Paulmurugan, A. Krishnan

The paper identifies enkurin as a novel marker of myeloproliferative neoplasms (MPNs) through analysis of platelet, megakaryocyte, and whole blood specimens, showing inverse association with CDC20 and involvement of calcium homeostasis and ER stress.

bioRxiv · Jan 7, 2023Cancer Biology

Paramagnetic spin labeling of a bacterial DnaB helicase for solid-state NMR

J. Zehnder, R. Cadalbert, M. Yulikov, G. Kuenze, T. Wiegand

This study labels a bacterial DnaB helicase with paramagnetic probes and uses solid-state NMR to determine distance restraints and confirm its hexameric structure.

bioRxiv · Sep 14, 2021Biophysics

Spectroscopic glimpses of the transition state of ATP hydrolysis trapped in a bacterial DnaB helicase

A. A. Malaer, N. Wili, L. A. Voelker, M. I. Kozlova, R. Cadalbert, A. Daepp, M. E. Weber, J. Zehnder, G. Jeschke, H. Eckert, A. Bockmann, D. Klose, A. Y. Mulkidjanian, B. H. Meier, T. Wiegand

The paper captures a late transition state of ATP hydrolysis in a bacterial helicase using NMR spectroscopy and identifies key interactions involving aluminum fluoride.

bioRxiv · Apr 8, 2021Biophysics

Biomolecular solid-state NMR spectroscopy at highest field: the gain in resolution at 1200 MHz

M. Calon, A. A. Malar, S. Pfister, V. Rimal, M. E. Weber, T. Wiegand, J. Zehnder, M. Chavez, R. Deb, R. Cadalbert, A. Dapp, M.-L. Fogeron, A. Hunkeler, L. Lecoq, A. Torosyan, , B. H. Meier

This paper demonstrates improved resolution in biomolecular solid-state NMR spectroscopy at 1200 MHz, showing higher peak resolution in 13C spectra and aliphatic side-chain resonances in 1H spectra compared to 850 MHz.

bioRxiv · Mar 31, 2021 · PreprintBiophysics

SARS-CoV-2 ORF7b: is a bat virus protein homologue a major cause of COVID-19 symptoms?

M.-L. Fogeron, R. Montserret, J. Zehnder, M.-H. Nguyen, M. Dujardin, L. Brigandat, L. Cole, M. Ninot-Pedrosa, L. Lecoq, B. H. Meier, A. Bockmann

The paper investigates whether SARS-CoV-2 ORF7b, through its leucine zipper structure, disrupts cellular processes like heart rhythm and cell adhesion, potentially causing COVID-19 symptoms.

bioRxiv · Feb 5, 2021 · PreprintBiochemistry

Comparison of the Accula SARS-CoV-2 Test with a Laboratory-Developed Assay for Detection of SARS-CoV-2 RNA in Clinical Nasopharyngeal Specimens

C. A. Hogan, N. Garamani, A. S. Lee, J. K. Tung, M. K. Sahoo, C. Huang, B. Stevens, J. Zehnder, B. A. Pinsky

This study compares the Accula SARS-CoV-2 POC test with a lab-developed assay, finding high negative agreement but lower positive agreement for low viral load samples.

bioRxiv · May 12, 2020Microbiology