Author

Jack Barr

AstraZeneca (Sweden)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Burcu BestasiD· 1 shared Danielle L. PatersoniD· 1 shared Dmitrii DegteviD· 1 shared Doris HellerschmiediD· 1 shared Farnusch KaschaniiD· 1 shared Francesca BottanelliiD· 1 shared Gina SimoniD· 1 shared Grzegorz SienskiiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Burcu BestasORCID

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2 papers

Recent·Most cited

Induced degradation of SNAP-fusion proteins

Savina Abraham Pol, Sara Liljenberg, Jack Barr, Gina Simon, Luis Wong-Dilworth, Danielle L. Paterson, Vladimir P. Berishvili, Francesca Bottanelli, Farnusch Kaschani, Markus Kaiser, Mariell Pettersson, Doris Hellerschmied

This paper develops SNAP-PROTACs to induce degradation of SNAP-fusion proteins, enabling selective depletion and functional analysis of target proteins.

RSC Chemical Biology · Jan 1, 2024Peer-reviewedCell Biology

Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing

Martin Peterka, Nina Akrap, Songyuan Li, Sandra Wimberger, Pei-Pei Hsieh, Dmitrii Degtev, Burcu Bestas, Jack Barr, Stijn van de Plassche, Patricia Mendoza-García, Saša Šviković, Grzegorz Sienski, Mike A. Firth, Marcello Maresca

This paper develops two prime editing strategies using DSB repair to improve genomic insertion efficiency and purity, expanding the prime editing toolkit.

Nature Communications · Mar 24, 2022Peer-reviewedMolecular Biology