Author

Jacob D. DeSchepper

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Timothy Wesley HandiD· 2 shared Aaron Yang· 1 shared Ali T. Rai· 1 shared Amanda C. PoholekiD· 1 shared Amanda ReshkeiD· 1 shared Anthony J. ZeleznikiD· 1 shared Antonija KolobariciD· 1 shared Austin J. Frazer· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Timothy Wesley HandORCID

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2 papers

Recent·Most cited

The microbiota extends the reproductive lifespan by safeguarding the ovarian reserve

Sarah K. Munyoki, Julie P. Goff, Amanda Reshke, Erin Wilderoter, Nyasha Mafarachisi, Antonija Kolobaric, Yi Sheng, Steven J. Mullett, Gabrielle E. King, Jacob D. DeSchepper, Richard J. Bookser, Carlos A. Castro, Stacy L. Gelhaus, Mayara Grizotte-Lake, Kathleen E. Morrison, , Eldin Jašarević

This study shows that the microbiota influences reproductive lifespan by maintaining the ovarian reserve through short chain fatty acids and gene regulatory networks.

bioRxiv · Sep 13, 2024 · PreprintDevelopmental Biology

Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

Darryl Adelaide Abbott, Ali T. Rai, Aaron Yang, Yixuan Cai, Shelcie Fabre, Austin J. Frazer, Jacob D. DeSchepper, Amanda C. Poholek, Timothy Wesley Hand

This study shows that maternal IgA suppresses Enterobacteriaceae colonization and prevents the development of intestinal microbiota-specific CD4+ T cells in neonates.

bioRxiv · Jun 10, 2024 · PreprintImmunology