Timothy Wesley Hand

This study shows that a microbiome-dependent mechanism increases MHC-II expression in colon cancer cells, enhancing immunotherapy response and limiting metastasis.

This study compares the pathogenic potential of classical and hypervirulent K. pneumoniae strains producing the K2 capsule, revealing differences in tissue tropism and mucoidy despite similar capsule production.

The paper develops MicFLY, a flow cytometry method to quantify and characterize intestinal microbiota at the single-cell level, revealing E. coli unbound by IgG and IgA is associated with necrotizing enterocolitis.

This study shows that the microbiota influences reproductive lifespan by maintaining the ovarian reserve through short chain fatty acids and gene regulatory networks.

This study shows that maternal IgA suppresses Enterobacteriaceae colonization and prevents the development of intestinal microbiota-specific CD4+ T cells in neonates.