Kathleen E. Morrison

Preconception stress in mice alters maternal behavioral, neural, and endocrine outcomes, and produces sex-specific disruptions in offspring

This study shows that pubertal stress in mice affects maternal behavior, HPA axis function, and offspring behavior, with sex-specific impacts.

Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamus

This study shows that stress during puberty and pregnancy alters histone acetylation regulators in the hypothalamus, leading to a blunted stress response.

The microbiota extends the reproductive lifespan by safeguarding the ovarian reserve

This study shows that the microbiota influences reproductive lifespan by maintaining the ovarian reserve through short chain fatty acids and gene regulatory networks.

The impact of pubertal stress and adult hormone exposure on the transcriptome of the developing hypothalamus

This study investigates how pubertal stress and adult hormone exposure affect the transcriptome of the developing hypothalamus in mice, identifying sex-specific changes in immediate early gene expression.

Circadian rhythms in the gut microbiota shape sex differences in host gene expression and metabolism

This study shows that microbial circadian rhythms influence sex differences in host gene expression and metabolism, with diet affecting these sex-specific patterns.

Colonization at birth with human CST IV cervicovaginal microbiota alters development and increases neonatal mortality in mice

The paper shows that colonization with nonoptimal human cervicovaginal microbiota in mice leads to developmental issues and increased neonatal mortality.

It’s the fiber, not the fat: Significant effects of dietary challenge on the gut microbiome

This study shows that dietary fiber, not fat, drives gut microbiota changes when comparing refined diets to chow in mice, with sex and age effects observed.

Epididymal glucocorticoid receptors promote intergenerational transmission of paternal stress

This study identifies epididymal glucocorticoid receptors as mediators of paternal stress effects on offspring through changes in extracellular vesicle miRs.