Author

Jacqueline M. Fabius

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Danielle L. SwaneyiD· 3 shared Manon EckhardtiD· 3 shared Mehdi BouhaddouiD· 3 shared Alicia RichardsiD· 2 shared Benjamin J. PolaccoiD· 2 shared Gwendolyn Μ. JangiD· 2 shared Helene FoussardiD· 2 shared Jiewei XuiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Danielle L. SwaneyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Paracrine Signals from HIV-1 Infected Immune Cells Reprogram Cervical Cancer Pathways

Charles Ochieng’ Olwal, Ujjwal Rathore, Sara K. Makanani, Prashant Kaushal, Immy A. Ashley, Manisha R. Ummadi, Vincent Appiah, Alexandra Lindsey Djomkam Zune, Sophie F. Blanc, Doug Winters, Yennifer Delgado, Kapten Muthoka, Jacqueline M. Fabius, Manon Eckhardt, Robyn M. Kaake, , Mehdi Bouhaddou

This study shows HIV-1 infected immune cells alter cervical cancer pathways through paracrine signals, with upregulated PI3K-AKT and interferon-stimulated genes.

iScience · Jun 1, 2026Peer-reviewedCancer Biology

Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories

Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Benjamin J. Polacco, Lucy Thorne, Manisha R. Ummadi, Chengjin Ye, Romel Rosales, Adrian Pelin, Jyoti Batra, Gwendolyn Μ. Jang, Jiewei Xu, Jack M. Moen, Alicia Richards, Yuan M. Zhou, Bhavya Harjai, , Nevan J. Krogan

The paper systematically analyzes proteomic and genomic data of SARS-CoV-2 variants to identify how mutations affect viral gene expression, host interactions, and immune evasion.

bioRxiv · Oct 19, 2022 · PreprintSystems Biology

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

David Ezra Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Hüttenhain, Robyn M. Kaake, Alicia Richards, Beril Tutuncuoglu, , Natalia Jura

Affinity-purification mass spectrometry of 26 SARS-CoV-2 proteins in HEK293T cells yields 332 high-confidence host interactions and 67 druggable human proteins with known compounds.

Nature · Apr 30, 2020Peer-reviewedSystems Biology✦ In-depth digest