Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through PIEZO1
Shawn M. Gillespie, Yoon Seok Kim, Anna C. Geraghty, Belgin Yalçın, Rebecca A. Mancusi, Jared D. Hysinger, Alexis English Ivec, James E. Reed, Richard Drexler, Michael A. Quezada, Karen E. Malacon, Pamelyn J. Woo, Christopher Mount, Aerin Yang, Mable Lam, , Michelle Monje
This study identifies the NLGN3-CSPG4-PIEZO1 axis as a regulator of glial precursor cell state and glioma proliferation through mechanosensitive signaling.
bioRxiv · Jul 12, 2025 · PreprintNeuroscience