Mable Lam

This study identifies activity-dependent exocytosis in mature oligodendrocytes as a mechanism driving myelin remodeling necessary for adult learning.

This study identifies the NLGN3-CSPG4-PIEZO1 axis as a regulator of glial precursor cell state and glioma proliferation through mechanosensitive signaling.

This study identifies SRF as a transcriptional regulator of cytoskeletal genes in oligodendrocytes essential for myelination during development.

This study shows that calcium signaling in oligodendrocytes is critical for shaping myelin sheath morphology during myelination in the developing mouse CNS.

This study identifies VAMP2/3-mediated exocytosis as essential for CNS myelin membrane expansion, revealing a pathway critical for myelin formation and potential therapeutic targeting.