Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine
Shweta Jain, Andrew G. Yee, James Maas, Sarah Gierok, Hongfei Xu, Jasmine A Stansil, Jacob Eriksen, Alexandra Nelson, Kätlin Silm, Christopher Ford, Robert H. Edwards
This study identifies AP-3 and VPS41 as factors that promote high-frequency dopamine release by targeting VMAT2 to axons and producing specialized synaptic vesicles.
Proceedings of the National Academy of Sciences · Oct 9, 2023Peer-reviewedNeuroscience