Jen Davis

Combining Anion Exchange and Size Exclusion Chromatography for Extracellular Vesicle Enrichment from Small Volumes of Human and Mouse Plasma for Quantitative Proteomics

This paper develops and validates a SEC-SAX protocol for enriching extracellular vesicles from small plasma volumes for quantitative proteomics in human and mouse samples.

Skeletal muscle TDP-43 aggregation drives progressive motor dysfunction and neurodegeneration with potential for functional recovery after clearance

This study shows that TDP-43 aggregation in skeletal muscle causes motor dysfunction and neurodegeneration, but clearance of the protein allows for functional recovery.

Human melanoma cell lines that possess wild-type BRAF alleles but are dependent on ERBB4 and ERBB2

This study investigates the role of ERBB4 heterodimers in driving the proliferation of BRAF-WT&RAS/NF1-mutant melanoma cell lines and shows that dominant-negative mutants of ERBB2 and EGFR inhibit clonogenic growth in some but not all cell lines.