Author

Jesun Lee

Cedars-Sinai Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Anjaparavanda P. NareniD· 2 shared Alvin Jay FreemaniD· 1 shared Ameet Shetty· 1 shared Anil Goud JeggaiD· 1 shared Appakalai N. BalamuruganiD· 1 shared Danielle HutchingsiD· 1 shared Gary A. SulikowskiiD· 1 shared Hongyu LiuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Anjaparavanda P. NarenORCID

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Author profile →

2 papers

Recent·Most cited

Photoaffinity ligand of Cystic Fibrosis corrector VX-445 identifies SCCPDH as an off-target

Minsoo Kim, Kwangho Kim, Jesun Lee, Lea A. Barny, Toya D. Scaggs, Ian M. Romaine, KyuOk Jeon, Simona G. Codreanu, Stacy D. Sherrod, JOHN A. JUN. MCLEAN, Anjaparavanda P. Naren, Gary A. Sulikowski, Lars Plate

The paper identifies SCCPDH as an off-target of VX-445 using a photoaffinity ligand and chemoproteomics, showing metabolic dysregulation and potential clinical implications.

ACS Chemical Biology · Jun 20, 2025Peer-reviewedBiochemistry

Differential Expression and Microsystem Physiology Reveal Predominant and Drug Reversible CFTR-Related Defects in Idiopathic Pancreatitis

Paba Edisuriya, Pramodha S. Liyanage, Jesun Lee, Ameet Shetty, Hongyu Liu, Nicholas P. Tatonetti, Danielle Hutchings, Alvin Jay Freeman, Jaimie D. Nathan, Appakalai N. Balamurugan, Stephen Jacob Pandol, Anil Goud Jegga, Anjaparavanda P. Naren, Kavisha Arora

This study identifies CFTR-related defects in idiopathic pancreatitis and shows that ivacaftor can reverse these defects in patient-derived models.

bioRxiv · May 25, 2025 · PreprintPathology