JOHN A. JUN. MCLEAN

This study engineers obligate anaerobic bacteria to tolerate oxygen, improving their survival in the gut.

This study shows dehydration increases intracellular lipid synthesis and accumulation by promoting glutamine oxidation and mitochondrial metabolic remodeling.

This paper evaluates the effectiveness of Bacillus species as biocontrol agents against Phytophthora capsici in tomato, using mass spectrometry imaging to analyze molecular interactions.

This study shows how ETBF reprograms host metabolism to create an oxidative niche that supports its growth in the inflamed gut.

The paper identifies SCCPDH as an off-target of VX-445 using a photoaffinity ligand and chemoproteomics, showing metabolic dysregulation and potential clinical implications.

The paper shows that a diet rich in L-amino acids overrides genetic resistance in mice, promoting Salmonella Typhimurium ileal colonization through microbiota-dependent mechanisms.

This study shows that ATP10A deficiency in female mice leads to dyslipidemia and hepatic insulin resistance without affecting weight gain on a high-fat diet.

The paper shows that increased antioxidant capacity in BRAF-mutated melanoma cells reduces sensitivity to BRAF inhibitors and suggests targeting redox pathways could improve treatment outcomes.