Jiangning Liu

Myristoylation licenses disordered viral VP4 protein to anchor to and perforate the membrane through phase separation

This study shows that myristoylation of VP4 enables membrane anchoring, phase separation, and pore formation in enteroviruses through multiple functional roles.

Characterization of bronchiolitis and vaccine-induced enhanced respiratory disease in Syrian hamsters caused by respiratory syncytial virus infection

This study characterizes RSV infection and vaccine-induced ERD in Syrian hamsters, showing age-dependent viral replication, pathological changes, and ERD responses similar to humans.

Mitotic bookmarking by Prox1 preserves mammalian neuronal lineage identity memory via promoting timely H3K27me3 restoration

This paper shows that Prox1 acts as a mitotic bookmark in mouse hippocampal neural stem cells to preserve neuronal lineage identity by promoting H3K27me3 restoration.

Lmna deficiency promotes EPHX2 nuclear translocation to ameliorate cardiac dysfunction in mice

This paper identifies EPHX2 nuclear translocation as a mechanism to ameliorate cardiac dysfunction in Lmna-deficient mice using AAV-Cas9-based gene editing.