Author

Jie Han

Radboud University Nijmegen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna Castells‐NobauiD· 1 shared Annette SchenckiD· 1 shared Boyd van ReijmersdaliD· 1 shared Carl NathaniD· 1 shared Chiara Pignato· 1 shared Daniel J. PfauiD· 1 shared Franziska KampshoffiD· 1 shared Garry HuangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Anna Castells‐NobauORCID

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2 papers

Recent·Most cited

The evolutionarily conserved EHMT1/G9a histone methyltransferase family regulates sleep maintenance through ROS homeostasis in insulin-producing cells

Mireia Coll-Tané, Lara V. van Renssen, Nicholas Raun, Jie Han, Núria Ribas-Ros, Boyd van Reijmersdal, Jenny Luong, Chiara Pignato, Franziska Kampshoff, Naihua Natalie Gong, Spencer G. Jones, Sigrid Pillen, Anna Castells‐Nobau, Jordi Mayneris‐Perxachs, Marieke Klein, , Annette Schenck

This study identifies EHMT1/G9a's role in sleep regulation through ROS homeostasis in insulin-producing cells, linking it to sleep disturbances in Kleefstra syndrome and common insomnia.

bioRxiv · Sep 3, 2026 · PreprintGenetics

Mycobacterium tuberculosis, Mycobacterium kansasii and Rhodococcus equi induce macrophage necroptosis in the presence of a caspase inhibitor acting on a non-canonical target(s)

Rong Hu, Pei Li, Jie Han, Jiamin Huang, Garry Huang, Xiuju Jiang, Daniel J. Pfau, Guobao Li, Yinan Gong, Carl Nathan, Li Zhang

This study shows that z-VAD induces necroptosis in macrophages infected with Mtb, M. kansasii, and R. equi by acting on non-canonical targets, and MLKL deficiency reduces TB pathology in susceptible mice.

bioRxiv · Sep 2, 2025 · PreprintMicrobiology