Author

Joe Faryean

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:CRISPR screen· 1 Assay:electrophysiology· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alessandra ChesiiD· 1 shared Alexandra NelsoniD· 1 shared Allison E. GirasoleiD· 1 shared Bao Khanh TrangiD· 1 shared Matthew Hoffman· 1 shared Michael RyaniD· 1 shared Natalia M. TulinaiD· 1 shared Pamela F. MarcottiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenetics

Alessandra ChesiORCID

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Author profile →

2 papers

Recent·Most cited

Integration of Alzheimer's GWAS, 3D genomics, and single-cell CRISPRi non-coding screen implicates causal variants in a microglial enhancer regulating TSPAN14.

Shannon Laub, Natalia M. Tulina, Matthew Hoffman, Joe Faryean, Sandhya Ramachandran, Bao Khanh Trang, Stephanie M. Lewkiewicz, Alessandra Chesi

The American Journal of Human Genetics · May 26, 2026Peer-reviewedGenetics

Repetitive Levodopa Treatment Drives Cell Type-Specific Striatal Adaptations Associated With Progressive Dyskinesia in Parkinsonian Mice

Rodrigo Manuel Paz, Michael Ryan, Pamela F. Marcott, Allison E. Girasole, Joe Faryean, Vincent Duong, Sadhana Sridhar, Alexandra Nelson

This study shows that repeated levodopa treatment in Parkinsonian mice leads to striatal adaptations, specifically enhanced glutamatergic synapses on D1-MSNs and reduced D2R sensitivity, which contribute to worsening dyskinesia.

bioRxiv · May 16, 2025 · PreprintNeuroscience