Author
Children's Hospital of PhiladelphiaORCID 0000-0002-9434-508XUnclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Kyla D. Mace, Bao Khanh Trang, Amber J. Zimmerman…·Matthew S. Kayser
The paper identifies EGR2 as a conserved sleep regulator by analyzing sub-threshold genetic signals across sleep-related traits in multiple species.
Shannon Laub, Natalia M. Tulina, Matthew Hoffman…·Alessandra Chesi
Amber J. Zimmerman, Samaneh Biglari, Bao Khanh Trang…·Alex C. Keene
The paper identifies cell-type-specific genes regulating sleep by mapping GWAS variants to effector genes in human and Drosophila models, revealing ruby/AP3B2 as a conserved glial regulator.
Mitchell Conery, James A. Pippin, Yadav Wagley…·Struan F.A. Grant
The paper integrates GWAS data with a CRISPRi screen in osteoblasts to identify genes affecting bone mineral density and reveals pleiotropy across non-bone tissues.
Rong Qiu, Bao Khanh Trang, Carson Shalaby…·Christopher S. Thom
The paper uses in vitro hematopoiesis systems to analyze gene expression and chromatin organization during HPC formation, identifying genetic impacts on blood traits and disease.
Bao Khanh Trang, Alessandra Chesi, Sylvanus Toikumo…·Struan F.A. Grant
This paper identifies shared and unique chromatin accessibility and 3D interactions of SUD loci, implicating non-neural cell types like pancreatic β-cells and showing a causal link between T2D and AUD.
Sheridan H. Littleton, Bao Khanh Trang, Christina M. Volpe…·Struan F.A. Grant
The paper identifies rs7132908 as a causal variant in the chr12q13 obesity locus, showing it affects FAIM2 expression and neurodevelopment through cis-regulatory mechanisms.