Author

Sugako Ogushi

The Francis Crick InstituteORCID 0000-0001-8497-6972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Aki ShiraishiiD· 1 shared Alexander Kurze· 1 shared Aurélien CourtoisiD· 1 shared Bin HuiD· 1 shared Daniel M. SnelliD· 1 shared Fanny Decarpentrie· 1 shared Hiroshi KiyonariiD· 1 shared James CollieriD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Aki ShiraishiORCID

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2 papers

Recent·Most cited

Genome editing of marsupial RSX reveals conserved and divergent principles in mammalian X-inactivation

Aurélien Courtois, Sergio Menchero, Sugako Ogushi, Wazeer Varsally, S. M. Wood, Fanny Decarpentrie, Riko Yoshimi, Aki Shiraishi, Kenichi Inoue, Takaya Abe, John L. VandeBerg, Daniel M. Snell, Hiroshi Kiyonari, James M. A. Turner

This study uses CRISPR-Cas9 in opossums to show RSX is required for initiating X-inactivation, with divergent Polycomb regulation compared to eutherians.

bioRxiv · Jul 7, 2026 · PreprintGenomics

The cohesin ring uses its hinge to organize DNA using non-topological as well as topological mechanisms

Madhusudhan Srinivasan, Johanna C. Scheinost, Naomi J Petela, Thomas G. Gligoris, Maria F. Wissler, Sugako Ogushi, James Collier, Menelaos Voulgaris, Alexander Kurze, Kok‐Lung Chan, Bin Hu, Vincenzo Costanzo, Kim Nasmyth

The paper investigates how cohesin organizes DNA through both topological and non-topological mechanisms, showing that hinge domain mutations affect DNA entrapment and loading.

Cell · May 1, 2018Peer-reviewedMolecular Biology