Frédéric Beckouët

The paper shows that premature termination of transcription by RNA polymerase I limits rRNA production and that a mutant polymerase, SuperPol, reduces this termination, increasing rRNA output.

The paper shows that sister chromatid cohesion inhibits cohesin-mediated DNA loop expansion during G2 phase.

The paper investigates how transcription and cohesin complexes influence genome organization in yeast, showing transcription induces DNA borders and loops independently of SMC complexes.

This study shows that bacterial chromosomes can undergo chromatin assembly, activity, looping, and compartmentalization in yeast, driven by their sequence composition.

The paper investigates how Scc2, Smc3 acetylation, and Pds5 regulate cohesin-dependent chromatin loop expansion during the cell cycle.

The paper identifies Eco1's role in negatively regulating cohesin translocase activity during yeast mitosis, affecting DNA loop extrusion and chromosome folding.

This study shows Scc2/4 maintains cohesin on chromosomes during G1 by blocking a Wapl-independent release mechanism, but is unnecessary during S phase for establishing cohesion.