Author

John C. McAuliffe

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Dianne CoxiD· 2 shared Jiufeng LiiD· 2 shared John S. CondeelisiD· 2 shared Maja H. OktayiD· 2 shared Ben Z. StangeriD· 1 shared Camille L. DuraniD· 1 shared Chinmay R. Surve· 1 shared Christian Adkisson· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Dianne CoxORCID

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Author profile →

2 papers

Recent·Most cited

Tie2 signaling in the tumor microenvironment orchestrates breast cancer cell dissemination through TMEM doorways

Camille L. Duran, Chinmay R. Surve, Prachiben P. Patel, Jack Hirsch, Jiufeng Li, Xianjun Ye, Nicole D. Barth, Xiaoming Chen, Suryansh Shukla, George S. Karagiannis, John C. McAuliffe, David Entenberg, Dianne Cox, John S. Condeelis, Maja H. Oktay

This study identifies macrophage Tie2 signaling as critical for TMEM doorway-mediated vascular permeability and metastatic dissemination in breast cancer.

bioRxiv · Apr 29, 2026 · PreprintCancer Biology

TMEM Doorway Mediated Metastasis in Pancreatic Ductal Adenocarcinoma by Tie2 Signaling

Érika Pereira Zambalde, Lina A. Ariyan, Francisco Puerta-Martinez, Yu Quin Zhu, Priyanka Patil, Nicole C. Panarelli, Jiufeng Li, Yookyung Jung, Christian Adkisson, Jakeb S. S. M. Petersen, Dianne Cox, Hava Gil-Henn, Robert J. Eddy, Ben Z. Stanger, David R. Entenberg, , John C. McAuliffe

This study identifies TMEM doorways as a mechanism for metastasis in PDAC, showing Tie2 macrophages facilitate intravasation and that targeting Tie2 improves survival in mouse models.

bioRxiv · Dec 9, 2025 · PreprintCancer Biology