Author

Jonathan Scott

Newcastle University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. John SimpsoniD· 1 shared Adib Miraki FeriziD· 1 shared Amanda B FathiD· 1 shared Amirhossein VahidiiD· 1 shared Anindita RoyiD· 1 shared Anthony RostroniD· 1 shared April Rose FosteriD· 1 shared Ash HollandiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

A. John SimpsonORCID

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Author profile →

2 papers

Recent·Most cited

Predicting how perturbations reshape cellular trajectories with PerturbGen

Kevin Chi Hao Ly, Adib Miraki Feriz, Tomoya Isobe, Amirhossein Vahidi, Delshad Vaghari, Anthony Rostron, Mariana Quiroga Londoño, Nicole Mende, M. S. Vijayabaskar, Marie Moullet, April Rose Foster, Emily J Graves, Fereshteh Torabi, Chloe Admane, David Horsfall, , Mohammad Lotfollahi

PerturbGen predicts how genetic perturbations affect cellular trajectories across time in human datasets, showing effects on immune responses, hematopoiesis, and skin development.

bioRxiv · Mar 5, 2026 · PreprintBioinformatics

Enhancement of mediodorsal thalamus rescues aberrant belief dynamics in a mouse model with schizophrenia-associated mutation.

Tingting Zhou, Yi-Yun Ho, Ray X. Lee, Amanda B Fath, Kathleen He, Jonathan Scott, Navdeep Bajwa, Nolan D. Hartley, Jonathan J. Wilde, Xian Gao, Li Cui, Evan Hong, Matthew R. Nassar, Ralf D. Wimmer, Tarjinder Singh, , Guoping Feng

This study identifies the mediodorsal thalamus as critical for belief dynamics in a schizophrenia mouse model and shows that enhancing its activity rescues cognitive deficits.

bioRxiv · Jan 8, 2024 · PreprintNeuroscience