Acetylation mimetic and null mutations within the filament core of P301L tau have varied effects on susceptibility to seeding and aggregation
Ethan D. Smith, Jose Torrellas, Robert McKenna, Quan Vo, Mario Mietzsch, David Borchelt, Stefan Prokop, Paramita Chakrabarty
This study examines how acetylation and phosphorylation mutations affect tau aggregation and seeding in Alzheimer's and PSP models.
Journal of Neurochemistry · Sep 1, 2025Peer-reviewedNeuroscience