Author

Joy Wu

Purdue University West Lafayette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Shalini T. Low-NamiD· 2 shared Alex J Alonzo· 1 shared Amber L. MosleyiD· 1 shared Andrew Walke· 1 shared Ankona DattaiD· 1 shared Brittany L. Allen-PeterseniD· 1 shared Brittany N. HeiliD· 1 shared Claire M. PfefferiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Shalini T. Low-NamORCID

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2 papers

Recent·Most cited

Direct measurement of PIP2 densities in biological membranes using a peptide-based sensor

Vinay K. Menon, Joy Wu, Alex J Alonzo, Kevin L. Scrudders, Kaitlyn A. Rogers, Suriya Selvarajan, Andrew Walke, Jennifer Pellicier-Caraballo, Rajasree Kundu, Samsuzzoha Mondal, Ankona Datta, Shalini T. Low-Nam

The paper develops a peptide-based sensor to measure PI(4,5)P2 densities in membranes, showing mutation-specific changes in surface levels in cells with Ras mutations.

Journal of Biological Chemistry · Oct 16, 2025Peer-reviewedBiochemistry

PP2A activation drives aberrant macropinocytosis and cell death in pancreatic ductal adenocarcinoma

Garima Baral, Claire M. Pfeffer, Sara N. Filippelli, Indiraa Doraivel, Brittany N. Heil, Lauren E. Gartenhaus, Kasi Hansen, Joy Wu, Goutham Narla, Emma H. Doud, Amber L. Mosley, Shalini T. Low-Nam, Brittany L. Allen-Petersen

This study shows that PP2A activation inhibits macropinocytosis and induces cell death in pancreatic ductal adenocarcinoma, suggesting PP2A activators could be used with metabolic inhibitors as a new therapeutic strategy.

bioRxiv · Jul 14, 2025 · PreprintCancer Biology