Author

Julia Derk

University of Colorado Anschutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Julie A. SiegenthaleriD· 3 shared Bradley T. PawlikowskiiD· 2 shared Kelly S. DoraniD· 2 shared Luke R. JoyceiD· 2 shared Amanda BradyiD· 1 shared Anna KremeriD· 1 shared Brady L. SpenceriD· 1 shared Christina N. ComoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Julie A. SiegenthalerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Meningeal inflammation and arachnoid barrier breakdown in a mouse model of neonatal bacterial meningitis

Sol Kim, Luke R. Joyce, Amanda Brady, Brady L. Spencer, Bradley T. Pawlikowski, Julia Derk, Kelly S. Doran, Julie A. Siegenthaler

This study shows that GBS infection increases arachnoid barrier permeability in neonatal mice, driven by cytokine production from fibroblasts and macrophages.

bioRxiv · Mar 5, 2026 · PreprintNeuroscience

Newly discovered base barrier cells provide compartmentalization of choroid plexus, brain and CSF

Daan Verhaege, Clint De Nolf, Jonas Castelein, Wouter Claeys, Elien Van Wonterghem, Griet Van Imschoot, Pieter Dujardin, Ward De Spiegelaere, Esther Hoste, Fleur Boone, Hart G.W. Lidov, Dani Neil, Julia Derk, Anna Kremer, Evelien Van Hamme, , Roosmarijn E. Vandenbroucke

The paper identifies a novel fibroblast subtype in the choroid plexus that forms a barrier between the choroid plexus stroma, brain, and cerebrospinal fluid.

bioRxiv · Jul 8, 2024 · PreprintNeuroscience

Formation and function of the meninges arachnoid barrier around the developing brain

Julia Derk, Christina N. Como, Hannah E. Jones, Luke R. Joyce, Stephanie K. Bonney, Rebecca O’Rourke, Bradley T. Pawlikowski, Kelly S. Doran, Julie A. Siegenthaler

The paper identifies Wnt-β-catenin signaling repression as key to arachnoid barrier cell specification in mouse meninges and shows its role in preventing pathogen entry during development.

bioRxiv · Jun 10, 2022 · PreprintDevelopmental Biology