Author

Jun Xie

Central South University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1 Organism:mouse· 1

Frequent Co-Authors

Alisha M. GruntmaniD· 1 shared April Destefano· 1 shared Chunwei ZhengiD· 1 shared Debora Pires-FerreiraiD· 1 shared Erik J. SontheimeriD· 1 shared Guangping GaoiD· 1 shared Haoyang ChengiD· 1 shared Jenny Gao· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

Alisha M. GruntmanORCID

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2 papers

Recent·Most cited

NanoLoop: A deep learning framework leveraging Nanopore sequencing for chromatin loop prediction

Wenjie Huang, Li Tang, Matthew C. Hill, Yonghao Zhang, Jun Xie, Min Li

NanoLoop predicts genome-wide chromatin loops using Nanopore sequencing data, identifying methylation patterns that influence loop types and reveal new long-range interactions.

Advanced Science · Feb 13, 2026Peer-reviewedBioinformatics

A Compact Base Editor Rescues AATD-associated Liver and Lung Disease in Mouse Models

Jenny Gao, Nathan Bamidele, Debora Pires-Ferreira, Chunwei Zheng, April Destefano, Haoyang Cheng, Qiushi Tang, Yueying Cao, Jun Xie, Guangping Gao, Alisha M. Gruntman, Erik J. Sontheimer, Terence R. Flotte, Wen Xue

This paper demonstrates that a compact ABE corrects the PiZ mutation in AATD mouse models, reducing liver disease and improving lung function.

Molecular Therapy · Aug 28, 2025Peer-reviewedBioengineering