Neuronal glucose metabolism sets cholinergic tone and controls thermo-regulated signaling at the neuromuscular junction
Y. Tang, H. Zong, H. Kwon, Y. Qiu, J. B. Pessin, L. Wu, K. A. Buddo, I. Boykov, C. Schmidt, C.-T. Lin, P. D. Neufer, G. J. Schwartz, I. J. Kurland, J. E. Pessin
This study shows that increasing glycolysis in cholinergic neurons boosts acetylcholine levels, reduces blood pressure and heart rate, and improves cold resistance.
eLife · Mar 7, 2022Peer-reviewedCell Biology